Application of Monoclonal Antibodies to Develop Rapid Immunoassays for Vibrio vulnificus: A Mini Review
نویسندگان
چکیده
Vibrio vulnificus (V. vulnificus) infection is a disease with serious health implications. Notably there are only about 50 confirmed cases of V. vulnificus per year but, the severity of the disease that is caused by this organism makes it the most pathogenic Vibrio. The organism is infamously associated with shellfish especially raw oysters and this could lead to the abated consumer confidence regarding the safety of the shellfish and could directly impact the shellfish industry. In the case of V. vulnificus, conventional methods are available to identify and enumerate this pathogen in oysters, but they are labor-intensive and time consuming. To maintain a constant supply of safe oysters, rapid and sensitive detection methods are required. Application of species-specific monoclonal antibody (MAB) could increase the sensitivity and speed of V. vulnificus detection by eliminating enrichment steps. This review discusses the recent advances in the area of antibody based V. vulnificus detection strategies.
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